Spravato Clinic
Treatment for adults with treatment-resistant depression & depressive symptoms
Available at our Parker and Colorado Springs Locations
What is Spravato?
The U.S. Food and Drug Administration approved Spravato (esketamine) nasal spray, in conjunction with an oral antidepressant, for the treatment of depression in adults who have tried other antidepressant medicines but have not benefited from them (treatment-resistant depression).
Esketamine is made from a drug called ketamine, an anesthetic that has also been used for many years to treat depression. But it wasn’t until recently that esketamine, a more potent version of ketamine, earned FDA approval specifically for use as a nasal spray for those with treatment-resistant depression.
How To Administer Spravato
With the nasal spray, you give yourself three doses, spaced five minutes apart, under provider supervision. You remain in the clinic under provider observation until potential side effects have passed.
Esketamine must be used in conjunction with a conventional antidepressant. The intention is that esketamine provides rapid relief from depression symptoms until the other medication takes effect.
What Do Treatments Look Like?
Usually, the treatment is given twice a week for the first month, and then if it is successful it is continued at decreased frequency in a maintenance phase for a few weeks or months with dosing and frequency determined by treatment response. Typically, this might mean a decrease to weekly treatments, then every two weeks, then monthly, etc.
You and your provider will discuss recommendations.
How Does It Work?
Esketamine works in a similar fashion, but unlike other antidepressants it increases levels of glutamate, the most abundant chemical messenger in the brain. The result? A greater impact on more brain cells at one time.
How Effective Is It?
Common antidepressants are slow-acting. It often takes several weeks to make a noticeable difference in how people with depression feel, says Kaplin. On the other hand, esketamine immediately impacts brain cells, offering relief from depressive symptoms within hours.
Your healing journey awaits
Treatments take place in a calm, comfortable, and carefully monitored environment designed to help you feel safe and at ease. Soft lighting, soothing surroundings, and attentive clinical support create a relaxing experience that allows you to fully focus on rest and reflection. Throughout the process, our Medical Assistants remain present for a supportive experience rather than clinical. Spravato treatment is both a medical service and a restorative experience that prioritizes what you need every step of the way.
Questions About Sparavato?
Reach out today for more information.